Interface in English. Medical references retain their original language; bilingual names and selected translations are provided.
工具说明
原始资料可追溯英文登记说明
Provides R wrappers of several on-target and off-target scoring methods for CRISPR guide RNAs (gRNAs). The following nucleases are supported: SpCas9, AsCas12a, enAsCas12a, and RfxCas13d (CasRx). The available on-target cutting efficiency scoring methods are RuleSet1, RuleSet3, DeepHF, enPAM+GB, and CRISPRscan. Both the CFD and MIT scoring methods are available for off-target specificity prediction. The package also provides a Lindel-derived score to predict the probability of a gRNA to produce indels inducing a frameshift for the Cas9 nuclease. Note that DeepHF and enPAM+GB are not available on Windows machines.
- 运行方式
- 访问原站或下载软件
- 登记许可
- MIT
- 核验状态
- 登记资料已同步 · 功能未验证
即将离开本站。原站对数据的处理规则以其政策为准。
方法与适用范围
来源为 bio.tools 登记记录，未逐项完成实际运行验证。请在上传数据或安装前核查作者、权限与许可。
依据与来源
- bio.tools 原始登记记录
元数据来源许可：CC BY 4.0；软件本身许可另行核查。中文说明为本站领域导引，不是完整翻译。