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中英关联术语

未折叠蛋白反应

Unfolded Protein Response

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A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS.

中文名称索引;定义为 MeSH 英文原文,尚未逐条译审。MESH:D056811 · MeSH 2026。

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