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中英关联术语

免疫球蛋白类型转换

Immunoglobulin Class Switching

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Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.

中文名称索引;定义为 MeSH 英文原文,尚未逐条译审。MESH:D017578 · MeSH 2026。

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