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中英关联术语

ADCC作用

Antibody-Dependent Cell Cytotoxicity

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The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a killer cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.

中文名称索引;定义为 MeSH 英文原文,尚未逐条译审。MESH:D000920 · MeSH 2026。

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